Noticias, Cursos y Seminario


CMA BíoBío contribuye a la génesis de información para más de 50 publicaciones científicas
Desde 2011 a mayo de 2015, el CMA BíoBío ha contribuido con nuestras tecnologías de punta en la obtención de datos para la publicación de 56 publicaciones científicas.
El listado de las publicaciones se encuentra a continuación, desglosadas por año:
2011 Las publicaciones de este año son las obtenidas por trabajos en el equipo Nikon Eclipse
1. Cifuentes M, García MA, Arrabal PM, Martínez F, Yañez MJ, Jara N, Weil B, Domínguez D, Medina RA, Nualart F. Insulin regulates GLUT1-mediated glucose transport in MG-63 human osteosarcoma cells. J Cell Physiol. 2011 Jun; 226(6):1425-32.
2. Cortés-Campos C, Elizondo R, Llanos P, Uranga RM, Nualart F, García MA. MCT expression and lactate influx/efflux in tanycytes involved in glia-neuron metabolic interaction. PLoS One. 2011 Jan 28;6(1)
3. Cuevas ME, Haensgen H, Sepúlveda FJ, Zegers G, Roa J, Opazo C, Aguayo LG. Soluble Aβ(1-40) peptide increases excitatory neurotransmission and induces Epileptiform activity in hippocampal neurons.J Alzheimers Dis. 2011;23(4):673-87
4. Fuentealba J, Dibarrart AJ, Fuentes-Fuentes MC, Saez-Orellana F, Quiñones K, Guzmán L, Perez C, Becerra J, Aguayo LG. Synaptic failure and adenosine triphosphate imbalance induced by amyloid-β aggregates are prevented by blueberry-enriched polyphenols extract. J Neurosci Res. 2011 Sep;89(9):1499-508.
5. Low M, Sandoval D, Morales B, Nualart F, Henríquez JP. Up-regulation of The vitamin C transporter SVCT2 upon differentiation and depolarization of myotubes.FEBS Lett. 2011 Jan 21; 585(2):390-6.
6. Maldonado-Agurto R, Toro G, Fuentealba J, Arriagada C, Campos T, Albistur M, Henriquez JP, Olate J, Hinrichs MV, Torrejón M.Cloning and spatiotemporal expression of RIC-8 in Xenopus embryogenesis.Gene Expr Patterns. 2011 Oct;11(7):401-8.
7. Nunez-Parra A, Cortes-Campos C, Bacigalupo J, Garcia Mde L, Nualart F, Reyes JG.b Expression and distribution of facilitative glucose (GLUTs) and monocarboxylate/H+ (MCTs) transporters in rat olfactory epithelia.Chem Senses. 2011 Nov;36(9):771-80.
8. Peters C, Muñoz B, Sepúlveda FJ, Urrutia J, Quiroz M, Luza S, De Ferrari GV, Aguayo LG, Opazo C. Biphasic effects of copper on neurotransmission in rat hippocampal neurons. 0J Neurochem. 2011 Oct;119(1):78-88.
2012
1. Juan Pablo Henríquez ."The vitamin C transporter SVCT2 is down-regulated during postnatal development of slow skeletal muscles" submitted to Journal of Histochemistry and Cell Biology".
2. Reinicke, K., Sotomayor, P., Cisterna, P., Delgado, C., Nualart, F., Godoy A. (2012). Cellular distribution of GLUT1 and GLUT5 in beningn and malignant prostate tissue. Journal of Cellular Biochemistry 113:553-562.
3. Orellana JA, Sáez P, Cortés-Campos C, Elizondo RJ, Shoji K, Contreras-Duarte S, Figueroa V, Velarde V, Jiang J, Nualart F, Sáez JC, García MA. (2012) Glucose increases intracellular free Ca(2+) in tanycytes via ATP released through connexin 43 hemichannels. GLIA 60:53-68.
4. Balmaceda-Aguilera, C., Cortés-Campos, C., Cifuentes, M., Peruzzo, B., Mark, L., Tapia, JC., Oyarce, K., García, MA., Nualart, F. (2012). Glucose transporter 1 and monocarboxylates transporters 1, 2 and 4 localization within the glial cells of shark blood-brain-barrier. PlosOne 7:e32409.
5. Nualart F, Castro T, Low M, Henríquez JP, Oyarce K, Cisterna P, García A, Bertinat R, Yáñez A, Montecinos V, García-Robles MA. (2012). Dynamic expresión of the sodium-vitamin C cotransporters, SVCT1 and SVCT2, Turing perinatal development. Histochemistry and Cell Biology Sep 19. [Epub ahead of print].
6. Bertinat R, Gatica R, San Martín R, Silva P, Caelles C, Slebe JC, Nualart F, Yáñez A. (2012). Altered expression and localization of insulin receptor in proximal tubule cells from human and rat diabetic kidney. (in press).
7. Marcellini S, Henriquez JP, Bertin A. Control of osteogenesis by the canonical Wnt and BMP pathways in vivo: Cooperation and antagonism between the canonical Wnt and BMP pathways as cells differentiate from osteochondroprogenitors to osteoblasts and osteocytes. Bioessays 2012, 3(11):953-62.
8. Benavente F. Pinto C., Parada M., Henriquez JP. Amd Osses N. Bone morphogenic protein 2 inhibits neurite outgrowth of motor neuron-like NSC-34 cells and up-regulates its type II receptor. J. Neurochem, 2012, 122 594-604.
9. Nualart F, Castro T, Low M, Henríquez JP, Oyarce K, Cisterna P, García A, Bertinat R, Yáñez A, Montecinos V, García-Robles MA. (2012). Dynamic expresión of the sodium-vitamin C cotransporters, SVCT1 and SVCT2, during perinatal development. Histochem. Cell Biol. 2013, 139 (2):233-47.
10. Nualart F, Salazar K, Oyarce K, Cisternas P, Jara N, Silva-Alvarez C, Pastor P, Martínez F, García A, García-Robles MA, Tapia JC. (2012). Typical and atypical stem cells in the brain, vitamin C effect and neuropathology. Biol Res. 2012;45(3):243-56.
11. Gatica R, Bertinat R, Silva P, Carpio D, Ramirez MJ, Slebe JC, San Martín R, , Nualart F, Campistol JM, Caelles C, , , Yáñez A. (2012). Altered expression and localization of insulin receptor in proximal tubule cells from human and rat diabetic kidney. J Cell Biochem. 2012 11:639-649.
12. Sandoval D, Ojeda J, Low M, Nualart F, Marcellini S, Osses N, Henríquez JP. The vitamin C transporter SVCT2 is down-regulated during postnatal development of slow skeletal muscles. Histochem Cell Biol. 2013 Jan 18. [Epub ahead of print].
13. Castro PA, Figueroa M, Yevenes GE, San Martin LS, Alguayo L. The basic property of Lys385 is important for potentiation of the human α1 glycine receptor by ethanol. J Pharmacol Expe. 2012; 340 (2): 339-49.
14. Fuentealba J, Dibarrart A, Saez-Orellana F, Fuentes M.C., Oyanedel CN, Guzmán JL, Perez C, Becerra J, Aguayo L. Synaptic Sylencing and plasma membrane Dyshomeostasis Induced by Amyloid-b Peptide are Prevented by Aristotelia chilensis Enriched Extract. J. Alzheimer Disease 31 (2012): 879-889
2013
1. Zurita MP, Muñoz G, Sepúlveda FJ, Gómez P., Castillo C, Burgos CF, Fuentealba J, Opazo C, Aguayo LG. Ibuprofen Inhibits the Synaptic Failure Induced by the Amyloid-β Peptide in Hippocampal Neurons. J Alzheimers. 2013 Jan 1;35(3):463-73.
2. Cortes-Campos C, Elizondo R, Carril C, Martınez F, Boric K, Nualart F, Garcia MA. MCT2 Expression and Lactate Influx in Anorexigenic and Orexigenic Neurons of the Arcuate Nucleus. Plos One Vol 8 (4): e62532, 2013.
3. Ulloa V, García-Robles M, Martínez F, Salazar K, Reinicke K, Pérez F, Godoy DF, Godoy AS, Nualart F. Human choroid plexus papilloma cells efficiently transport glucose and vitamin C. J Neurochem. 2013 May 7. doi: 10.1111/jnc.12295. [Epub ahead of print] PMID:23647458.
4. Antileo E, Garri C, Tapia V, Muñoz JP, Chiong M, Nualart F, Lavandero S, Fernández J, Núñez MT. Endocytic pathway of exogenous iron-loaded ferritin in intestinal epithelial (Caco-2) cells. Am J Physiol Gastrointest Liver Physiol. 2013 Apr 1;304(7):G655-61. doi: 10.1152/ajpgi.00472.2012.
5. Vera A, Stanic K, Montecinos H, Torrejón M, Marcellini S, Caprile T. SCO-spondin from embryonic cerebrospinal fluid is required for neurogenesis during early brain development. Front Cell Neurosci. 2013 Jun 3,; Vol 7:80.
6. Peters. C, Fernandez-Perez E, Burgos C, Espinosa MP, Castillo C, Urrutia JC, Streltsov V, Opazo C, Aguayo L. Inhibition of amyloid beta-induced synaptotoxicity by a pentapeptide derived from the glycine zipper región of the neurotoxic peptide. Neurbiology of Aging 34 (2013) 2805-2814.
7. Pastor P, Cisternas P, Salazar K, Silva-Alvarez C, Oyarce K, Jara N, Espinoza F, Martinez A, Nualart F. SVCT2 vitamin C transporter expression in progenitor cells of the postnatal neurogenic niche. Front Cell Neurosci. 2013 Aug 13;7:119.doi:10.3389/fncel.2013.00119.
8. Fuentealba J, Toro-Tapia G, Arriagada C, Riquelme L, Beyer A, Henriquez JP, Caprile T, Mayor R, Marcellini S, Hinrichs MV, Olate J, Torrejón M. Ric-8A a guanine nucleotide Exchange factor for heterotrimeric G proteins, is critical for cranial neural crest migration. Dev Biol. 2013 Jun 15;378(2):74-82. doi: 10.1016/j.ydbio.2013.04.005.
9. Rodríguez FS, Salazar KA, Jara NA, García-Robles MA, Pérez F, Ferrada LE, Martínez F, Nualart FJ. Superoxide-dependent uptake of vitamin C in human glioma cells. J Neurochem. 2013 Jul 13. doi: 10.1111/jnc.12365. [Epub ahead of print].
10. Pinto C, Cárdenas P, Osses N, Henríquez JP. Characterization of Wnt/β-catenin and BMP/Smad signaling pathways in an in vitro model of amyotrophic lateral sclerosis. Front Cell Neurosci. 2013 Dec 3; 7:239.
11. Montoya F, Martínez F., García-Robles M., Balmaceda-Aguilera C., Koch X., Rodríguez F., Silva-Álvarez C., Salazar K., Ulloa V., Nualart F. Clinical and experimental approaches to knee cartilage lesión repair and mesenchymal stem cell chondrocyte differentiation. Biol. Res. 46 No 4, 2013.
2014
1. Sepúlveda FJ, Fierro H, Fernández E, Castillo C, Peoples RW, Opazo C, Aguayo LG. Nature of the neurotoxic membrane actions of amyloid-B on hippocampal neurons in Alzheimer´s disease. Neurobiol Aging. 2014 Mar; 35(3):472-81.
2. Mariqueo T., Agurto A, Muñoz B, San Martín L., Coronado C., Fernández-Pérez F., Murath P., Sánchez A, Homantics G., Aguayo LG. J. Neurophysiol. Published 26 February 2014.
3. Cisternas P., Silva-Álvarez C., Martínez F., Fernández E., Ferrada L., Oyarce K., Salazar K., Bolaños JP., Nualart F. The oxidized form of vitamin C, dehydroascorbic acid, regulates neuronal energy metabolism. J. Neurochem. Jan 25, 2014.
4. Oyarce, K., Nualart, F. Unconventional neurogenic niches and neurogenesis modulation by vitamins. Stem Cell Research and Therapy. 4. 3-10. 2014.
5. Salgado M, Tarifeño-Saldivia E, Ordenes P, Millan C, Yañez MJ, Llanos P, Villagra M, Elizondo-Vega R, Martinez R, Nualart F, Uribe E, Garcia-Robles MA. Dynamic localization of glucokinase and its regulatory protein in hypothalmaic tanycytes. PLoS One. 2014; 9(4):e94035.
6. Retamal M, Alcayaga J, Bultynck G, Leybaer L, Saez P, Fernandez R, Leon L, Saez J. The opening of connexin and pannexin hemichannels increases the excitability of nodose ganglion sensory neurons. Front Cell Neurosci. 2014 Jun 20;8:158. doi: 10.3389/fncel.2014.00158. eCollection 2014.
7. Araya JA, Ramírez AE, Figueroa-Aroca D, Sotes GJ, Pérez C, Becerra J, Saez-Orellana F, Guzmán L, Aguayo LG, Fuentealba J. Modulation of Neuronal Nicotinic Receptor by Quinolizidine Alkaloids Causes Neuroprotection on a Cellular Alzheimer Model J Alzheimers Dis. 2014;42(1):143-55.
8. Stanic K, Vera A, Gonzalez M, Recabal A, Astuya A, Torrejon M, Montecinos H, Caprile T. Complementary expression of EphA7 and SCO-spondin during posterior commissure development. Frontiers in Neuroanatomy.Front Neuroanat. 8:49, 2014
9. Valdes P, Mercado G, Vidal R, Molina C, Parsons G, Court F, Martinez A, Galleguillos D, Armentano D, Schneider B, Hetz C. Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1. PNAS
10. Salazar K, Cerda G, Martinez F, Sarmiento J, Gonzalez C, Rodriguez F, Garcia-Robles MA, Tapia JC, Cifuentes M, Nualart F. SVCT2 transporter expression is post-natally induced in cortical neurons and its function is regulated by its short isoform. J. Neurochem. J Neurochem. 130:693-709. 2014.
11. Castro PA, Ramirez A, Sepúlveda FJ, Peters C, Fierro H, Waldron J, Luza S, Fuentealba J, Muñoz FJ, De Ferrari GV, Bush AI, Aguayo LG, Opazo CM. Copper-uptake is critical for the down regulation of synapsin and dynamin induced by neocuproine: modulation of synaptic activity in hippocampal neurons. Front Aging Neurosci. 2014 Dec 3;6:319.
12. Morales JC, Alvarez-Ferradas C, Roncagliolo M, Fuenzalida M, Wellmann M, Nualart FJ, Bonansco C. A new rapid kindling variant for induction of cortical epileptogenesis in freely moving rats. Front Cell Neurosci. 2014 Jul 23;8:200.
13. Nualart, F., Mack, L., García, A., Cisternas, P., Borgarzone, ER., Heitzer, M., Jara, N., Martínez, F., Espinoza, F., Ferrada, L., Baeza, V., Salazar, K. (2014). Vitamin C transporters, recycling and the Bystander effect in the nervous system: SVCT2 versus GLUTs. Journal of Stem Cell Research and Therapy. 4(5):209.
14. Avilés EC, Pinto C, Hanna P, Ojeda J, Pérez V, De Ferrari GV, Zamorano P, Albistur M, Sandoval D, Henríquez JP. Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells. Front Cell Neurosci. 2014 Apr 17;8:110.
15. Fernández A, Guzmán S, Cruz Y, Zamorano P.Construction of bicistronic lentiviral vectors for tracking the expression of CDNF in transduced cells. Plasmid. 2014 Sep 10;76C:15-23.
2015
1. Bertinat R, Silva P, Mann E, Li X, Nualart F, Yáñez AJ. In vivo Sodium Tungstate Treatment Prevents E-Cadherin Loss Induced by Diabetic Serum in HK-2 Cell Line. J Cell Physiol. 2015 Feb 28. doi: 10.1002/jcp.24974.
2. Castillo R del P, Araya J, Troncoso E, Vinet S, Freer J. Fourier transform infrared imaging and microscopy studies of Pinus radiata pulps regarding the simultaneous saccharification and fermentation process. Anal Chim Acta. 2015 Mar 25;866:10-20.
3. Gatica R, Bertinat R, Silva P, Kairath P, Slebe F, Pardo F, Ramírez MJ, Slebe JC, Campistol JM,Nualart F, Caelles C, Yáñez AJ. Over-expression of muscle glycogen synthase in human diabetic nephropathy. Histochem Cell Biol. 2015 Mar;143(3):313-24.
4. Bertin A, Hanna P, Otarola G, Fritz A, Henriquez JP, Marcellini S. Cellular and molecular characterization of a novel primary osteoblast culture from the vertebrate model organism Xenopus tropicalis. Histochem Cell Biol. 2015 Apr;143(4):431-42.
5. Pacheco CR, Morales CN, Ramírez AE, Muñoz FJ, Gallegos SS, Caviedes PA, Aguayo LG, Opazo CM. Extracellular α-synuclein alters synaptic transmission in brain neurons by perforating the neuronal plasma membrane. J Neurochem. 2015 Mar;132(6):731-41.
6. Peters C, Espinoza MP, Gallegos S, Opazo C, Aguayo LG.Alzheimer's Aβ interacts with cellular prion protein inducing neuronal membrane damage and synaptotoxicity. Neurobiol Aging. 2015 Mar;36(3):1369-77.
7. Muñoz G, Urrutia JC, Burgos CF, Silva V, Aguilar F, Sama M, Yeh HH, Opazo C, Aguayo LG. Low concentrations of ethanol protect against synaptotoxicity induced by Aβ in hippocampal neurons.Neurobiol Aging. 2015 Feb;36(2):845-56.
8. Gatica, R., Bertinat, R., Silva, P., Kairath, P., Slebe, F., Pardo, F., Ramírez, M.J., Slebe, J.C., Campistol, J.M., Nualart, F., Guinovart, J.J., Caelles, C., Yañez, A.J. (2015) Overexpression of muscle glycogen synthase in human diabetic nephropathy. Histochem. Cell. Biol. (Accepted).
9. Campos T, Ziehe J, Palma M, Escobar D, Tapia JC, Pincheira R, Castro AF.Rheb promotes cancer cell survival through p27Kip1-dependent activation of autophagy. Mol Carcinog. 2015

Primera Reunión CMA Bío- Bío
El día miércoles 20 de Abril del 2011 se celebró la primera reunión del CMA Bío Bío. La reunión fue presidida por el Dr. Francisco Nualart, Director Científico del centro y contó con la participación del Sr. Decano de la Facultad de Ciencias Biológicas de la Universidad de Concepción, Profesor Nelson ... ver +
APLICACIONES DE LA ESPECTROSCOPÍA INFRARROJA EN EL ESTUDIO DE SISTEMAS BIOLÓGICOS: ECOLOGIA, TAXONOMIA Y BIODIVERSIDAD
Expositores Dr. Jaime Rodríguez Fernández. Colección Boliviana de Fauna – Doctor en Entomología, Universidad de Paraná, Curitiba, Brasil. Dra. Rosario Castillo Felices, Facultad de Farmacia, Centro de Biotecnología, Universidad de Concepción. 9:30- 10:15 hrs. Dr. Jaime Rodríguez Fernández. Fundamentos y aplicación de la espectroscopía en el infrarrojo cercano (NIRS) e infrarrojo medio (MIR) ... ver +


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Centro de Microscopía Avanzada,CMA Bío-Bío. Universidad de Concepción.
Barrio Universitario s/n. Edificio Ennio Vivaldi 2do. piso. Concepción, Chile.
Fonos: (56) 41-2204531, (56) 41-2203479,(56) 41-2661356 - Fax (56) 41-2245975.
contacto@cmabiobio.cl - www.cmabiobio.cl